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SEXUALLY TRANSMITTED DISEASES (STDs) during PREGNANCY

CANDIDIASIS
  • caused by the fungus Candida, women notices thick, cheese like vaginal discharge, and extreme pruritus.
  • more frequent during pregnancy because of increased estrogen level. other women experience this because of antibiotic therapy, gestational DM, with HIV.
  • important to be treated during pregnancy before delivery with local antifungal agent (nystatin suppositories) since it can be transmitted vaginally.
TRICHOMONIASIS
  • caused by trichomonas vaginalis; women notices yellow gray vaginal discharge adhering to vaginal walls.
  • associated with preterm labor.
  • drug of choice is metronidazole (Flagyl), which can be teratogenic during first trimester.
BACTERIAL VAGINOSIS (Gardnerella infection)
  • caused by gardnerella or bulimus curtsii organisms; woman notices gray discharge with fish-like odor.
  • pregnant women treated with ampicillin or amoxicillin- the safest drug of choice.
CHLAMYDIA TRACHOMATIS
  • most common during pregnancy with heavy gray-white vaginal discharge; diagnosis made by culture; women are screened by the first prenatal visit and by third trimester.
  • associated with premature rupture of membrane, preterm labor, and endometritis during post partum. Infant can suffer from conjunctivitis and pneumonia following birth.
  • tetracycline is contraindicated during pregnancy; but amoxicillin or erythromycin can be used.
SYPHILIS
  • a systemic disease caused by treponema pallidum.
  • first stage is a painless vulvar ulcers; after 18th week spirochete crosses the placenta and may cause preterm labor, stillbirth, or congenital anomalies in the newborn.
  • women are screened at the first prenatal visit, again at about 36th week, and once again during labor.
  • drug of choice is benzathine penicillin G; safe during pregnancy.
HERPES SIMPLEX VIRUS TYPE 2
  • woman develops painful, small pinpoint vesicles surrounded by erythema on the vulva or vagina.
  • can be transmitted across the placenta to cause congenital anomaly or vginally for congenital infections.
  • cesaran delivery is preferred. Drug of choice (acyclovir) is contraindicate during pregnancy; woman can reduce the pain by Sitz bathing.
GONORRHEA
  • caused by neisseria gonorrhea, which may not produce symptoms or a yellow green vaginal discharge may be present.
  • associated with spontaneous abortion, preterm delivery, and endometritis during post partum.
  • very important to be treated during pregnancy because it can cause blindness for infants after birth.
  • drug of choice is Ceftriaxone, and is safe during pregnancy.
HUMAN PAPILLOMA VIRUS
  • causes fibrous tissue overgrowth on the external vulva (condyloma acuminatum).
  • associated with cervical cancer; obstructs vaginal orifice and exposing infant to the infection; cesarean delivery is preferred.
  • lesions are treated and removed during post partum period.
GROUP B STREPTOCOCCI INFECTION
  • no apparent symptoms; associated with UTI, intraamniotic infection, and post partal endometritis.
  • can be transmitted through placenta or from direct contact in vaginal canal and caused pneumonia and meningitis.
  • women are screened and treated at 38th weeks aith either penicillin or erythromycin until delivery.
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