- The placenta is usually located posterior to the uterus on the intestine or in Douglas' cul-de-sac; which can infiltrate and erode major blood vessel in the abdomen leading to hemorrhage or peritonitis.
- Fetal outline is difficult to palpate; woman may feel no fetal movement or experience painful fetal movements.
- Past history of the woman includes previous uterine surgery or ectopic pregnancy.
- If reaches term, the infant has an increased incidence of fetal deformity and is delivered by laparotomy.
- Methotrexate is the drug of choice to destroy placental cells.